Tetracera forzzae Fraga & Aymard (Dilleniaceae), a new species from Brazil, is described and illustrated, and its relationships are discussed. The new species is morphologically related to T. empedoclea Gilg, T. portobellensis Beurling, and T. parviflora (Rusby) Sleumer; however, T. forzzae can be distinguished by its flowers with seven sepals, petals 7–8 mm long, and the leaves with simple and stellate trichomes on the adaxial surface. This new species is known only from the Zona da Mata of the state of Minas Gerais, and is the fourth Neotropical species of this genus so far discovered with a single carpel. According to the criteria of the IUCN Red List of endangered plant species this species is assigned to the EN (Endangered) category.